The profits will be slightly different but you need to take into account your losses during transfering between coins.
These include the following for most
Lets say you are mining BTCP but want BTC so you can cash out as you state you are running a business and need to pay the bills.
Transfer fee of BTCP to Exchange
Trade fee of BTCP to BTC
Capital gains tax for the trade
Transfer fee of BTC to an exchange to cash out to FIAT
NiceHash is normally only a few cents behind mining the coin outright in profitability. Lastly NiceHash doesn’t determine where your hash power goes. The buyers of your hashpower determine what pools to mine at. Nicehash is just a nice connection point between buyer and sellers. Think of them as Craigslist lol also check out this post I did where I broke down some of these numbers.